Orientation analysis of collagen fibers in skin by using polarization-resolved second-harmonic generation microscopy

Eiji Hase; Takeshi Yasui

doi:10.1117/12.2613415

7 March 2022 Orientation analysis of collagen fibers in skin by using polarization-resolved second-harmonic generation microscopy

Eiji Hase, Takeshi Yasui

Author Affiliations +

Proceedings Volume PC11934, Photonics in Dermatology and Plastic Surgery 2022; PC1193408 (2022) https://doi.org/10.1117/12.2613415
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Polarization-resolved second-harmonic-generation (PR-SHG) microscopy simultaneously visualizes the orientation angle and degree of crystallinity in collagen fibers in tissues. In this paper, we developed fast PR-SHG microscopy based on pixel-by-pixel rapid polarization switching applicable for in situ measurements of the human skin. The demonstrated results indicated that our system would be a powerful tool for optical assessment of dermal collagen fiber in cosmetics research.

Conference Presentation

Citation Download Citation

Eiji Hase and Takeshi Yasui "Orientation analysis of collagen fibers in skin by using polarization-resolved second-harmonic generation microscopy", Proc. SPIE PC11934, Photonics in Dermatology and Plastic Surgery 2022, PC1193408 (7 March 2022); https://doi.org/10.1117/12.2613415

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Collagen

Optical fibers

Skin

Microscopy

Second-harmonic generation

Polarization

Visualization

Show All Keywords

Keywords/Phrases

Search In:

Publication Years