Silver-chalcogenide nanoparticles as multi-modal theranostic agents for breast cancer (Conference Presentation)

David Cormode

doi:10.1117/12.2643536

17 March 2023 Silver-chalcogenide nanoparticles as multi-modal theranostic agents for breast cancer (Conference Presentation)

David Cormode

Author Affiliations +

Proceedings Volume PC12395, Colloidal Nanoparticles for Biomedical Applications XVIII; PC123950C (2023) https://doi.org/10.1117/12.2643536
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Silver chalcogenide nanoparticles are biocompatible, low cost and straightforward to synthesize. They have quantum dot-like optical properties, which have been used in imaging and therapeutic applications. We have found these nanoparticles to have strong x-ray contrast production, especially for mammography. We have also innovated in their synthesis by developing an ambient conditions, room temperature method, using a microfluidic chip, which results in nanoparticles that have almost complete clearance within 24 hours. Last, encapsulation in a biodegradable polymer matrix results in remarkable enhancement of the optical properties of these nanoparticles, allowing markedly improved optical imaging and photothermal ablation of breast cancer.

Conference Presentation

Citation Download Citation

David Cormode "Silver-chalcogenide nanoparticles as multi-modal theranostic agents for breast cancer (Conference Presentation)", Proc. SPIE PC12395, Colloidal Nanoparticles for Biomedical Applications XVIII, PC123950C (17 March 2023); https://doi.org/10.1117/12.2643536

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