Digital holographic microscopy for toxicity testing and cell culture quality control

Björn Kemper

doi:10.1117/12.2287652

23 February 2018 Digital holographic microscopy for toxicity testing and cell culture quality control

Björn Kemper

Proceedings Volume 10503, Quantitative Phase Imaging IV; 105031J (2018) https://doi.org/10.1117/12.2287652
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

For the example of digital holographic microscopy (DHM), it is illustrated how label-free biophysical parameter sets can be extracted from quantitative phase images of adherent and suspended cells, and how the retrieved data can be applied for in-vitro toxicity testing and cell culture quality assessment. This includes results from the quantification of the reactions of cells to toxic substances as well as data from sophisticated monitoring of cell alterations that are related to changes of cell culture conditions.

Citation Download Citation

Björn Kemper "Digital holographic microscopy for toxicity testing and cell culture quality control", Proc. SPIE 10503, Quantitative Phase Imaging IV, 105031J (23 February 2018); https://doi.org/10.1117/12.2287652

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