Bacteriostatic influence of red laser light on the growth of Staphylococcus aureus and photodynamic enhancement of this effect with Photoditazine

A. V. Egorova; G. E. Brill; I. O. Bugaeva; E. S. Tuchina; G. V. Ponomaryov; O. V. Ushakova

doi:10.1117/12.2313498

26 April 2018 Bacteriostatic influence of red laser light on the growth of Staphylococcus aureus and photodynamic enhancement of this effect with Photoditazine

A. V. Egorova, G. E. Brill , I. O. Bugaeva, E. S. Tuchina, G. V. Ponomaryov, O. V. Ushakova

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Proceedings Volume 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX; 1071612 (2018) https://doi.org/10.1117/12.2313498
Event: Saratov Fall Meeting 2017, 2017, Saratov, Russian Federation

Abstract

The influence of red laser irradiation on the growth of colonies of Staphylococcus aureus and photodynamic effect of the photosensitizer Photoditazine were performed. It was established that the emission of red laser light caused an inhibition of bacterial growth. This effect on standard strain of Staphylococcus aureus was evident only when relatively high doses of radiation (180 j/cm²). Photosensitivity of the methicillin-resistant strains was much higher: bacteriostatic effect of red light was observed already at the dose of 60 j/cm² . Pre-treatment of bacterial cells by Photoditazine significantly enhances the inhibitory effect of the laser light.

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A. V. Egorova, G. E. Brill , I. O. Bugaeva, E. S. Tuchina, G. V. Ponomaryov, and O. V. Ushakova "Bacteriostatic influence of red laser light on the growth of Staphylococcus aureus and photodynamic enhancement of this effect with Photoditazine", Proc. SPIE 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX, 1071612 (26 April 2018); https://doi.org/10.1117/12.2313498

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