Simulation analysis of the enhancement of asymmetric illumination-based differential phase contrast microscope

Cheng-Wei Ho; Snow H. Tseng

doi:10.1117/12.2507729

4 March 2019 Simulation analysis of the enhancement of asymmetric illumination-based differential phase contrast microscope

Cheng-Wei Ho, Snow H. Tseng

Author Affiliations +

Proceedings Volume 10887, Quantitative Phase Imaging V; 108870Z (2019) https://doi.org/10.1117/12.2507729
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

We report an effective approach to analyze the effect of different amplitude patterns on image quality of asymmetric illumination-based differential phase contrast (AIDPC) microscope. Specifically, we investigate how the amplitude pattern can enhance the imaging quality. Two types of amplitude patterns are tested by the pseudospectral time-domain (PSTD) simulation. Preliminary simulation show promising results. Furthermore, the reported simulation may enhance the AIDPC system by helping researchers to optimize the optical system and facilitate new optical imaging strategies on AIDPC imaging.

Conference Presentation

Citation Download Citation

Cheng-Wei Ho and Snow H. Tseng "Simulation analysis of the enhancement of asymmetric illumination-based differential phase contrast microscope", Proc. SPIE 10887, Quantitative Phase Imaging V, 108870Z (4 March 2019); https://doi.org/10.1117/12.2507729

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