Mesh-based and polycapillary optics-based x-ray phase imaging

Weiyuan Sun; Congxiao He; Carolyn A. MacDonald; Jonathan C. Petruccelli

doi:10.1117/12.2512628

1 March 2019 Mesh-based and polycapillary optics-based x-ray phase imaging

Weiyuan Sun, Congxiao He, Carolyn A. MacDonald, Jonathan C. Petruccelli

Proceedings Volume 10948, Medical Imaging 2019: Physics of Medical Imaging; 109484U (2019) https://doi.org/10.1117/12.2512628
Event: SPIE Medical Imaging, 2019, San Diego, California, United States

Abstract

The contrast in conventional x-ray imaging is generated by differential attenuation of x rays, which is generally very small in soft tissue. Phase imaging has been shown to improve contrast and signal to noise ratio (SNR) by factors of 100 or more. However, acquiring phase images typically requires a highly spatially coherent source (e.g. a 50 μm or smaller microfocus source or a synchrotron facility), or multiple images acquired with precisely aligned gratings. Here we demonstrate two phase imaging techniques compatible with clinical sources: polycapillary focusing optics to enhance source coherence and mesh-based structured illumination.

Citation Download Citation

Weiyuan Sun, Congxiao He, Carolyn A. MacDonald, and Jonathan C. Petruccelli "Mesh-based and polycapillary optics-based x-ray phase imaging ", Proc. SPIE 10948, Medical Imaging 2019: Physics of Medical Imaging, 109484U (1 March 2019); https://doi.org/10.1117/12.2512628

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