Visible light optical coherence tomography angiography (vis-OCTA) in human retina for small vessel blood oxygenation (Conference Presentation)

Weiye Song; Steven Ness; Manishi Desai; Ji Yi

doi:10.1117/12.2549090

9 March 2020 Visible light optical coherence tomography angiography (vis-OCTA) in human retina for small vessel blood oxygenation (Conference Presentation)

Weiye Song, Steven Ness, Manishi Desai, Ji Yi

Author Affiliations +

Proceedings Volume 11218, Ophthalmic Technologies XXX; 112180A (2020) https://doi.org/10.1117/12.2549090
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Although vis-OCT oximetry has been successfully demonstrated in vivo in human retina, it is so far limited on large vessels. To precisely locate the small vessels in depth dimension, OCTA is the natural method since it can effectively enhance the vessel contrast. In this paper, we demonstrate the first visible OCTA image in human retina, the small blood vessel can be located with high fidelity by using both the structural and angiographic contrasts. This technical advance lays a foundation for the absolute sO2 calculation in small vessels in human retina in order to assess local oxygen extraction and metabolism.

Conference Presentation

Citation Download Citation

Weiye Song, Steven Ness, Manishi Desai, and Ji Yi "Visible light optical coherence tomography angiography (vis-OCTA) in human retina for small vessel blood oxygenation (Conference Presentation)", Proc. SPIE 11218, Ophthalmic Technologies XXX, 112180A (9 March 2020); https://doi.org/10.1117/12.2549090

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