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20 April 2020 Characterizing intestinal obstruction using a photoacoustic-ultrasound catheter (Conference Presentation)
Yunhao Zhu, Linyu Ni, Laura Johnson, Jie Yuan, Xueding Wang, Peter Higgins, Guan Xu
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Proceedings Volume 11240, Photons Plus Ultrasound: Imaging and Sensing 2020; 112401L (2020) https://doi.org/10.1117/12.2544305
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
Photoacoustic (PA) imaging has shown its capability of characterizing intestinal inflammation and fibrosis endoscopically. With the purpose of clinical translation, we developed an endoscopic probe integrating an intracardiac ultrasound array and an 800 µm side-firing fiber optic inside a medical balloon catheter. The catheter probe, when collapsed, fits to the instrument channel of a colonoscope and can inflate for acoustic coupling when positioned at the disease location inside intestine. The performance of the probe in assessing the disease conditions including inflammation, fibrosis and muscle hypertrophy is under investigation in rabbits in vivo. The imaging results are validated by histopathology.
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Yunhao Zhu, Linyu Ni, Laura Johnson, Jie Yuan, Xueding Wang, Peter Higgins, and Guan Xu "Characterizing intestinal obstruction using a photoacoustic-ultrasound catheter (Conference Presentation)", Proc. SPIE 11240, Photons Plus Ultrasound: Imaging and Sensing 2020, 112401L (20 April 2020); https://doi.org/10.1117/12.2544305
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KEYWORDS
Inflammation
Diagnostics
Endoscopy
Acoustic coupling
Biopsy
Fiber optics
Photoacoustic imaging
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