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17 March 2020 An anisotropic model for evaluation of corneal elasticity in dynamic OCE (Conference Presentation)
Mitchell A. Kirby, John J. Pitre Jr., David S. Li, Tueng T. Shen M.D., Ruikang K. Wang, Matthew O'Donnell, Ivan M. Pelivanov
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Proceedings Volume 11242, Optical Elastography and Tissue Biomechanics VII; 112420T (2020) https://doi.org/10.1117/12.2544449
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
In assuming an isotropic model for soft-tissue, dynamic OCE can produce order of magnitude errors in Young’s modulus estimates relative to static mechanical tests. Considering corneal fiber arrangement, we propose a simplified transverse isotropic (TI) model of the cornea, which depends on moduli λ and μ and the independent modulus G (which affects the propagation of vertically polarized surface waves, such as those measured in OCE). Early theoretical and experimental studies suggest that this TI model of the cornea may greatly improve quantitative estimates of corneal mechanics obtained using dynamic OCE.
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Mitchell A. Kirby, John J. Pitre Jr., David S. Li, Tueng T. Shen M.D., Ruikang K. Wang, Matthew O'Donnell, and Ivan M. Pelivanov "An anisotropic model for evaluation of corneal elasticity in dynamic OCE (Conference Presentation)", Proc. SPIE 11242, Optical Elastography and Tissue Biomechanics VII, 112420T (17 March 2020); https://doi.org/10.1117/12.2544449
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KEYWORDS
Solid modeling
Cornea
Wave propagation
Elastography
Mechanics
Natural surfaces
Tissue optics
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