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9 March 2020 Controlled plasmonic cell fusion and its implications on the actin cytoskeleton (Conference Presentation)
Julia Belansky, Limor Minai, Dvir Yelin
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Proceedings Volume 11270, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XX; 112700A (2020) https://doi.org/10.1117/12.2544830
Event: SPIE LASE, 2020, San Francisco, California, United States
Abstract
Cell fusion is an important process that occurs during normal development, as well as during cancer growth and metastasis. Using specific gold nanoparticles and intense femtosecond laser pulses to induce plasmonic cell fusion, we study the reorganization of the actin network within the fused cells, network that is known to be highly involved in epithelial-mesenchymal transitions. Time-lapse confocal microscopy of the fused cells showed large-scale actin networks within the giant hybrid cells, with unique reorganization dynamics that preserve the original filament orientation of original cells.
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Julia Belansky, Limor Minai, and Dvir Yelin "Controlled plasmonic cell fusion and its implications on the actin cytoskeleton (Conference Presentation)", Proc. SPIE 11270, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XX, 112700A (9 March 2020); https://doi.org/10.1117/12.2544830
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KEYWORDS
Cytoskeletons
Plasmonics
Cancer
Femtosecond phenomena
Gold
Breast cancer
Confocal microscopy
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