Saliva characterization of eosinophilic esophagitis via surface enhanced Raman spectroscopy

Andrea K. Locke; Girish Hiremath; Regina Tyree; Anita Mahadevan-Jansen

doi:10.1117/12.2579054

5 March 2021 Saliva characterization of eosinophilic esophagitis via surface enhanced Raman spectroscopy

Andrea K. Locke, Girish Hiremath, Regina Tyree, Anita Mahadevan-Jansen

Proceedings Volume 11651, Optical Diagnostics and Sensing XXI: Toward Point-of-Care Diagnostics; 116510B (2021) https://doi.org/10.1117/12.2579054
Event: SPIE BiOS, 2021, Online Only

Abstract

Current diagnosis of pediatric eosinophilic esophagitis relies heavily on anesthesia and random biopsies during initial diagnosis and treatment monitoring. Investigation of patient’s saliva biochemical and biomolecular composition, and the potential biomarkers within, via surface enhanced Raman spectroscopy can provide key markers for distinguishing the EoE disease from non-EoE, including acid reflux disease. This optical modality coupled with paper-fluidic platform has the potential to provide a rapid diagnostic tool for non-invasive detection of EoE.

Conference Presentation

Citation Download Citation

Andrea K. Locke, Girish Hiremath, Regina Tyree, and Anita Mahadevan-Jansen "Saliva characterization of eosinophilic esophagitis via surface enhanced Raman spectroscopy", Proc. SPIE 11651, Optical Diagnostics and Sensing XXI: Toward Point-of-Care Diagnostics, 116510B (5 March 2021); https://doi.org/10.1117/12.2579054

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Surface enhanced Raman spectroscopy

Diagnostics

Biopsy

Control systems

Esophagus

Principal component analysis

Proteins

Show All Keywords

Keywords/Phrases

Search In:

Publication Years