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We present a method for large volume imaging of highly scattering tissues using a dual-axis optical coherence tomography system (DA-OCT) at 1.3 μm featuring a dynamic focus-tracking method to create an enhanced depth of focus. Our approach is validated for skin imaging, using an in vivo rat skin model. A quantitative discussion of imaging performance in highly scattering tissue for both DA-OCT and conventional OCT at 1.3 μm is presented.
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Evan T. Jelly, Hillel Price, Kengyeh K. Chu, Adam Wax, "Clinical readiness of dual-axis OCT for dermatology," Proc. SPIE 11657, Biomedical Applications of Light Scattering XI, 1165709 (5 March 2021); https://doi.org/10.1117/12.2577281