CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 11786 > Article
Presentation
25 June 2021 3D architected materials as scaffolds for cell growth
Maria Farsari
Author Affiliations +
Proceedings Volume 11786, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials V; 117861J (2021) https://doi.org/10.1117/12.2593275
Event: SPIE Optical Metrology, 2021, Online Only
Abstract
We present our latest work into the modelling and fabrication of 3D auxetic metamaterials, and their evaluation as scaffolds for cell growth. Auxetic metamaterials are materials that display a negative Poisson’s ratio; when stretched, they become thicker perpendicular to the applied force. Their properties are mainly due to their architecture, rather than their chemical composition. Natural biological tissues display auxetic characteristics in organs such as skin, artery, tendon, and cancellous bone. Auxetic porous materials facilitate mass transport and, therefore, there is potential for optimal flow or delivery of nutrients, metabolic wastes and therapeutic agents. Some of their potential application are as scaffolds for blood vessels, esophageal stents, skin grafts, scaffolds for artificial lungs and cardiac patches. To make these metamaterials scaffolds, we employ 3D multiphoton polymerisation (MPP) of photopolymers. This is a technique which allows the fabrication of 3D microstructures with sub-100 nm resolution. It is based on the phenomenon of multiphoton absorption (MPA). When the beam of an ultrafast laser tightly focused inside the volume of a transparent photopolymer, it can initiate polymerisation via MPA. Moving the beam in a three-dimensional manner will result in the direct writing of 3D structures inside the volume of the photopolymer. The material employed for the fabrication of the 3D metamaterial is a homemade zirconium silicate, known to be biocompatible. Finally, we investigate the suitability of these metamaterials as scaffolds for cell growth.
Conference Presentation
© (2021) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Maria Farsari "3D architected materials as scaffolds for cell growth", Proc. SPIE 11786, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials V, 117861J (25 June 2021); https://doi.org/10.1117/12.2593275
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Metamaterials
Photopolymers
Polymerization
Skin
Modeling
Silicates
Therapeutic agents
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top