Bio-optic gas visualization system (Sniff-cam) for human volatiles

Kohji Mitsubayashi; Kenta Iitani; Koji Toma; Takahiro Arakawa

doi:10.1117/12.2615689

27 October 2021 Bio-optic gas visualization system (Sniff-cam) for human volatiles

Kohji Mitsubayashi, Kenta Iitani, Koji Toma, Takahiro Arakawa

Proceedings Volume 11925, Biomedical Imaging and Sensing Conference 2021; 119250W (2021) https://doi.org/10.1117/12.2615689
Event: SPIE Technologies and Applications of Structured Light, 2021, Online, Japan

Abstract

A bio-optic gas-imaging system (sniff-cam) with enzyme immobilized mesh demonstrates a spatiotemporal gasimaging for human volatiles (i.e., ethanol, acetaldehyde, etc. after drinking). A bio-fluorometric technique was applied to improve the sensitivity of the gas visualization system. The bio-fluorometric sniff-cam for ethanol was constructed with alcohol dehydrogenase (ADH) immobilized mesh and the NADH imaging unit (UV-LED array and highly sensitive CMOS), thus imaging human ethanol in the gas phase not only exhaled air but also transcutaneous vapor after drinking. The sniffer system would be useful for detecting the volatile biomarkers.

Citation Download Citation

Kohji Mitsubayashi, Kenta Iitani, Koji Toma, and Takahiro Arakawa "Bio-optic gas visualization system (Sniff-cam) for human volatiles", Proc. SPIE 11925, Biomedical Imaging and Sensing Conference 2021, 119250W (27 October 2021); https://doi.org/10.1117/12.2615689

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