High speed 4D in-vivo OCT imaging of the human brain: creating high density datasets for machine learning toward identification of malign tissue in real time

Wolfgang Draxinger; Dirk Theisen-Kunde; Lion Schützeck; Nicolas Detrez; Paul Strenge; Veit Danicke; Jessica Kren; Patrick Kuppler; Sonja Spahr-Hess; Matteo Mario Bonsanto; Ralf Brinkmann; Robert Huber

doi:10.1117/12.2648505

16 March 2023 High speed 4D in-vivo OCT imaging of the human brain: creating high density datasets for machine learning toward identification of malign tissue in real time

Wolfgang Draxinger, Dirk Theisen-Kunde, Lion Schützeck, Nicolas Detrez, Paul Strenge, Veit Danicke, Jessica Kren, Patrick Kuppler, Sonja Spahr-Hess, Matteo Mario Bonsanto, Ralf Brinkmann, Robert Huber

Author Affiliations +

Proceedings Volume 12390, High-Speed Biomedical Imaging and Spectroscopy VIII; 123900D (2023) https://doi.org/10.1117/12.2648505
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Neuro-surgery is challenged by the difficulties of determining brain tumor boundaries during excisions. Optical coherence tomography is investigated as an imaging modality for providing a viable contrast channel. Our MHz-OCT technology enables rapid volumetric imaging, suitable for surgical workflows. We present a surgical microscope integrated MHz-OCT imaging system, which is used for the collection of in-vivo images of human brains, with the purpose of being used in machine learning systems that shall be trained to identify and classify tumorous tissue.

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Wolfgang Draxinger, Dirk Theisen-Kunde, Lion Schützeck, Nicolas Detrez, Paul Strenge, Veit Danicke, Jessica Kren, Patrick Kuppler, Sonja Spahr-Hess, Matteo Mario Bonsanto, Ralf Brinkmann, and Robert Huber "High speed 4D in-vivo OCT imaging of the human brain: creating high density datasets for machine learning toward identification of malign tissue in real time", Proc. SPIE 12390, High-Speed Biomedical Imaging and Spectroscopy VIII, 123900D (16 March 2023); https://doi.org/10.1117/12.2648505

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