Chromophore estimation from finite element derived skin tissue models: simulation and experiments

Vysakh Vasudevan; Sujatha Narayanan Unni

doi:10.1117/12.3007924

20 September 2023 Chromophore estimation from finite element derived skin tissue models: simulation and experiments

Vysakh Vasudevan, Sujatha Narayanan Unni

Proceedings Volume 12608, Biomedical Imaging and Sensing Conference; 1260811 (2023) https://doi.org/10.1117/12.3007924
Event: Optics and Photonics International Congress, 2023, Yokohama, Japan

Abstract

Chromophore estimation is vital in diagnosing structural and functional aspects of skin tissue. Diffuse reflectance spectroscopy aids the non-invasive determination of tissue chromophores. Here we present a finite element model of tissue diffuse reflectance for constructing a look-up table (LUT) with multiple source-to-detector separations, which can be used for the quantitative estimation of skin tissue melanin and haemoglobin content and was verified using in-vitro skin tissue phantoms. The statistical analysis demonstrated the applicability of the developed LUT and the inverse algorithm for chromophore estimation from skin layers.

Citation Download Citation

Vysakh Vasudevan and Sujatha Narayanan Unni "Chromophore estimation from finite element derived skin tissue models: simulation and experiments", Proc. SPIE 12608, Biomedical Imaging and Sensing Conference, 1260811 (20 September 2023); https://doi.org/10.1117/12.3007924

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