In this study, we demonstrated rapid microfluidic mixing using the photothermal properties of gold nanoisland films. By focusing laser beams on a gold nanoisland film, bubbles were successfully generated in a 100-μm-thick fluid chamber filled with non-degassed water. Air-rich and water vapor-rich bubbles were generated by simultaneously irradiating two laser spots. Although water was not degassed, the water vapor-rich bubble was held next to the air-rich bubble for more than 10s, during which time a strong flow was generated. As a result, an area with a diameter of 1.5-2mm around the laser spot was stirred for approximately 3s. This method requires only a laser and thin film and does not require fluid degassing, making the method a promising active micromixer with a simple structure.
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