Performance of an iterative reconstruction algorithm for near-infrared absorption and scatter imaging

Simon Robert Arridge; Martin Schweiger; Mutsuhisa Hiraoka; David T. Delpy

doi:10.1117/12.154654

14 September 1993 Performance of an iterative reconstruction algorithm for near-infrared absorption and scatter imaging

Simon Robert Arridge, Martin Schweiger, Mutsuhisa Hiraoka, David T. Delpy

Proceedings Volume 1888, Photon Migration and Imaging in Random Media and Tissues; (1993) https://doi.org/10.1117/12.154654
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

We have developed an iterative reconstruction algorithm for TOAST, based on a finite element method (FEM) forward model that is fast and very flexible. The algorithm can be used at present with either non-time-resolved and/or time-resolved data, and can reconstruct either (mu) _a and/or (mu) _s parameters. An equivalent version can be formulated in terms of phase shift and modulation frequency. The basis of the algorithm is to attempt to find the minimum error norm between the measured data and the forward model acting on the trial solution, by a `classical' non-linear search in the distribution of the (mu) _a and (mu) _s parameters. In principle any search strategy could be used, but the advantage of our approach is that it employs analytical results for the gradient change (partial)M/(partial)(mu) , where M is the measurement. A number of factors influence the performance of the algorithm -- sampling density of the data and solution, noise in the data, accuracy of the model, and appropriate usage of a priori information. It appears that the presence of local minima of the error norm surface cannot be ignored. This paper presents an analysis of the performance of the algorithm on data generated from the FEM model, and from an independent Monte-Carlo model.

Citation Download Citation

Simon Robert Arridge, Martin Schweiger, Mutsuhisa Hiraoka, and David T. Delpy "Performance of an iterative reconstruction algorithm for near-infrared absorption and scatter imaging", Proc. SPIE 1888, Photon Migration and Imaging in Random Media and Tissues, (14 September 1993); https://doi.org/10.1117/12.154654

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available