Radiosensitization by porphyrins in 60Co-irradiated cells of different natures

Zivile Luksiene; Vydmantas Atkocius

doi:10.1117/12.168687

1 March 1994 Radiosensitization by porphyrins in 60Co-irradiated cells of different natures

Zivile Luksiene, Vydmantas Atkocius

Proceedings Volume 2078, Photodynamic Therapy of Cancer; (1994) https://doi.org/10.1117/12.168687
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary

Abstract

Efficiency of cell radiosensitization by porphyrins is a function of the irradiation dose, the nature of the cell and physico-chemical properties of the sensitizer. The maximal radio- sensitization for E. ascites tumor cells was reached at 2 Gy, for Saccharomyces cerevisiae- 25Gy. The radiosensitization by different porphyrins in E.ascites tumor cells increases their cytotoxicity by a factor of 3, in Saccharomyces cerevisae --inhibition of growth 0.5 - 2.5 time.

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Zivile Luksiene and Vydmantas Atkocius "Radiosensitization by porphyrins in 60Co-irradiated cells of different natures", Proc. SPIE 2078, Photodynamic Therapy of Cancer, (1 March 1994); https://doi.org/10.1117/12.168687

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