Unique characteristics of optically recorded action potentials

Steven D. Girouard; Kenneth R. Laurita; David S. Rosenbaum M.D.

doi:10.1117/12.176576

26 May 1994 Unique characteristics of optically recorded action potentials

Steven D. Girouard, Kenneth R. Laurita, David S. Rosenbaum M.D.

Proceedings Volume 2132, Clinical Applications of Modern Imaging Technology II; (1994) https://doi.org/10.1117/12.176576
Event: OE/LASE '94, 1994, Los Angeles, CA, United States

Abstract

Voltage-sensitive dyes have been used to optically monitor cardiac transmembrane potential for almost twenty years. This method now permits mapping of cardiac activation and recovery with spatial resolution that is unattainable by conventional mapping techniques. Despite the growing use and potential advantages of optical mapping with voltage-sensitive dyes, little information is available regarding optical action potential signal characteristics. Thus, no accepted standards for recording optical action potentials exists (e.g., sampling rates, analog filtering requirements). This paper will review some of the unique characteristics of optically recorded cardiac action potentials.

Citation Download Citation

Steven D. Girouard, Kenneth R. Laurita, and David S. Rosenbaum M.D. "Unique characteristics of optically recorded action potentials", Proc. SPIE 2132, Clinical Applications of Modern Imaging Technology II, (26 May 1994); https://doi.org/10.1117/12.176576

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