Electrochemical sensors using supported bilayer lipid membranes

Angelica L. Ottova; Ding-li Guo; H. Ti Tien

doi:10.1117/12.174081

1 May 1994 Electrochemical sensors using supported bilayer lipid membranes

Angelica L. Ottova, Ding-li Guo, H. Ti Tien

Proceedings Volume 2189, Smart Structures and Materials 1994: Smart Materials; (1994) https://doi.org/10.1117/12.174081
Event: 1994 North American Conference on Smart Structures and Materials, 1994, Orlando, FL, United States

Abstract

Some electrical properties were studied on potential responses of self-assembled bilayer lipid membranes (s-BLMs). Gramicidin doped s-BLM sensors responded to hydrogen ion concentrations linearly with the slope of 144 mV/decade in the range of 0.4 to 4 M; Monensin doped s-BLM sensors responded to sodium ion, which has a slope of about 40 mV/decade in the concentration range of 0.3 to 30 mM; Valinomycin doped s-BLM sensors have nearly Nernstian response in the concentration range of 1.0 to 30 mM/[K+]; Ferrocene doped s-BLM sensors responded linearly to the ferricyanide ion, whose slope is 146 mV/decade in the concentration range of 0.03 to 30 mM/[K₃Fe(CN)₆]. Many ions such as ferrocyanide, citrate, SCN^-, ClO_{4/$(superscript -}, etc. did not interfere with the sensor response characteristics. Factors influencing s-BLM sensors' reproducibility and stability also were investigated.

Citation Download Citation

Angelica L. Ottova, Ding-li Guo, and H. Ti Tien "Electrochemical sensors using supported bilayer lipid membranes", Proc. SPIE 2189, Smart Structures and Materials 1994: Smart Materials, (1 May 1994); https://doi.org/10.1117/12.174081

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