Photophysical characterization of far-red absorbing photosensitizers in cyclodextrin solutions

Beate Roeder; Carsten Zimmermann; Ralf Herter

doi:10.1117/12.199181

12 January 1995 Photophysical characterization of far-red absorbing photosensitizers in cyclodextrin solutions

Beate Roeder, Carsten Zimmermann, Ralf Herter

Proceedings Volume 2325, Photodynamic Therapy of Cancer II; (1995) https://doi.org/10.1117/12.199181
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

One of the most important problems for clinical use of photodynamic therapy is the selective accumulation of photosensitizer molecules by the tumor tissue. Possibly cyclodextrins could be used to solubilize and transport hydrophobic dyes to the target. Until now it has not been investigated to what extent the dye-cyclodextrin complexation alters the photophysical properties of the dye molecules important for their photodynamic activity. For this reason we investigated the behavior of three sensitizers belonging to different chemical classes: pheophorbide a, octa-(alpha) -butyloxy-Zn-phthalocyanine, and tetra-tert-butyl-Zn- naphthalocyanine in cyclodextrin solutions.

Citation Download Citation

Beate Roeder, Carsten Zimmermann, and Ralf Herter "Photophysical characterization of far-red absorbing photosensitizers in cyclodextrin solutions", Proc. SPIE 2325, Photodynamic Therapy of Cancer II, (12 January 1995); https://doi.org/10.1117/12.199181

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available