Topical photodynamic therapy with 5-ALA in the treatment of arsenic-induced skin tumors

Sigrid Karrer; Rolf-Markus Szeimies; Michael Landthaler

doi:10.1117/12.203453

1 March 1995 Topical photodynamic therapy with 5-ALA in the treatment of arsenic-induced skin tumors

Sigrid Karrer, Rolf-Markus Szeimies, Michael Landthaler

Proceedings Volume 2371, 5th International Photodynamic Association Biennial Meeting; (1995) https://doi.org/10.1117/12.203453
Event: Fifth International Photodynamic Association Biennial Meeting, 1994, Amelia Island, FL, United States

Abstract

A case of a 62-year-old woman suffering from psoriasis who was treated orally with arsenic 25 years ago is reported. The cumulative dose of arsenic trioxide was 800 mg. Since 10 years ago arsenic keratoses, basal cell carcinomas, Bowen's disease and invasive squamous cell carcinomas mainly on her hands and feet have developed, skin changes were clearly a sequence of arsenic therapy. Control of disease was poor, her right little finger had to be amputated. Topical photodynamic therapy with 5-aminolevulinic acid was performed on her right hand. Clinical and histological examinations 6 months after treatment showed an excellent cosmetic result with no signs of tumor residue.

Citation Download Citation

Sigrid Karrer, Rolf-Markus Szeimies, and Michael Landthaler "Topical photodynamic therapy with 5-ALA in the treatment of arsenic-induced skin tumors", Proc. SPIE 2371, 5th International Photodynamic Association Biennial Meeting, (1 March 1995); https://doi.org/10.1117/12.203453

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