Fluorescence spectroscopy to evaluate dermal wounds

Yuanlong Yang; Lee David Mitchell; Robert R. Alfano

doi:10.1117/12.206812

12 April 1995 Fluorescence spectroscopy to evaluate dermal wounds

Yuanlong Yang, Lee David Mitchell, Robert R. Alfano

Proceedings Volume 2387, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II; (1995) https://doi.org/10.1117/12.206812
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

Fluorescence spectra of dermal lesions on 48 rats have been investigated using excitation wavelengths of 275 nm, 300 nm and 340 nm. Emission at 340 nm and 460 nm were measured in both forequarter and hindquarter lesions. Unlike 460 nm emission, intensity at 340 nm increased with time and then saturated. Control studies on intact skin and lesions in dead rats failed to demonstrate any time dependent changes. It appears that the 340 nm intensity changes is due to changes in the tryptophan level, and may reflect a factor in the wound healing process.

Citation Download Citation

Yuanlong Yang, Lee David Mitchell, and Robert R. Alfano "Fluorescence spectroscopy to evaluate dermal wounds", Proc. SPIE 2387, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II, (12 April 1995); https://doi.org/10.1117/12.206812

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