Novel algorithm to determine absorption and scattering coefficients from time-resolved measurements

Ruikang K. Wang; Yappa A.B.D. Wickramasinghe; Peter J. Rolfe

doi:10.1117/12.308182

13 May 1998 Novel algorithm to determine absorption and scattering coefficients from time-resolved measurements

Ruikang K. Wang, Yappa A.B.D. Wickramasinghe, Peter J. Rolfe

Proceedings Volume 3254, Laser-Tissue Interaction IX; (1998) https://doi.org/10.1117/12.308182
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States

Abstract

A novel algorithm is demonstrated to determine the reduced scattering and absorption coefficients from time-resolved reflectance measurements at two positions on the surface of biotissue. The algorithm is very straightforward and fast, in which only some simple mathematical operations are involved, avoiding complicated iterative non-linear fitting to the time- resolved curve. The derived reduced scattering coefficient is not affected by whatever boundary condition is applied. The algorithm was verified using the time-resolved data from the Monte-Carlo model. Both the semi-infinite medium and the turbid slab medium were tested. In contrast to the non-linear fitting method, it is found using this algorithm that both the scattering and absorption coefficients can be determined to a high accuracy.

Citation Download Citation

Ruikang K. Wang, Yappa A.B.D. Wickramasinghe, and Peter J. Rolfe "Novel algorithm to determine absorption and scattering coefficients from time-resolved measurements", Proc. SPIE 3254, Laser-Tissue Interaction IX, (13 May 1998); https://doi.org/10.1117/12.308182

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available