Restoring accommodation: surgical technique and preliminary evaluation in rabbits

Hassan Tahi; Pascal F. Chapon; Marie Hamaoui; William E. Lee; Brien Holden; Jean-Marie A. Parel

doi:10.1117/12.350583

18 June 1999 Restoring accommodation: surgical technique and preliminary evaluation in rabbits

Hassan Tahi, Pascal F. Chapon, Marie Hamaoui, William E. Lee, Brien Holden, Jean-Marie A. Parel

Proceedings Volume 3591, Ophthalmic Technologies IX; (1999) https://doi.org/10.1117/12.350583
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

Purpose. To evaluate an innovative surgical technique for phaco-ersatz, a cataract surgery designed to restore accommodation. Techniques for very small capsulorhexis as well as the refilling procedure were developed. This study evaluates the feasibility and reproducibility of the surgical technique. Methods. The right eye of 8 NZW rabbits (≈ 2 Kg) were operated following the ARVO Statements for the Use of Animals in Ophthalmic and Vision Research. The surgery is begun by making a small peripheral capsulorhexis of about 1 mm using. The lens content is then removed. The lens is then refilled with a novel in situ polymerizable gel and the corneal incision is closed using one 10/0 Nylon interrupted stitch. Results. The capsulorhexis technique was succesfully performed and reproducible in all animals. The average size of the capsulorhexis opening was 1. 2 mm (±0.14). Lens material removal and refilling of the capsular bag with an in situ polymerizable material was also performed in each trial study. Conclusion. This surgical technique seemed feasible and reproducible.

Citation Download Citation

Hassan Tahi, Pascal F. Chapon, Marie Hamaoui, William E. Lee, Brien Holden, and Jean-Marie A. Parel "Restoring accommodation: surgical technique and preliminary evaluation in rabbits", Proc. SPIE 3591, Ophthalmic Technologies IX, (18 June 1999); https://doi.org/10.1117/12.350583

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