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Thermal coagulation of biological tissue leads to a significant change of the scattering coefficient. We use continuous wave transillumination techniques to monitor this change process of rat liver in different constant temperature (55 approximately 95 degree(s)C). To our knowledge, this is the first experiment about dynamic investigation. Based on light intensity measured, the change of scattering coefficient as a function of time is deduced, which show that this method is valid to monitor thermotherapy.
Dan Zhu,Qingming Luo,Jiangsheng Yu,Shaoqun Zeng, andRuan Yu
"Coagulation process of biological tissue measured by light scattering", Proc. SPIE 3863, 1999 International Conference on Biomedical Optics, (17 September 1999); https://doi.org/10.1117/12.364421
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Dan Zhu, Qingming Luo, Jiangsheng Yu, Shaoqun Zeng, Ruan Yu, "Coagulation process of biological tissue measured by light scattering," Proc. SPIE 3863, 1999 International Conference on Biomedical Optics, (17 September 1999); https://doi.org/10.1117/12.364421