Laser-induced fluorescent endoscopy (LIFE) in detection of malignant lesions of the colon

Wojciech Cebula; Witold Zieleznik; Aleksander Sieron; Mariusz Adamek; Aleksandra Kawczyk-Krupka; Michal Szygula; Tomasz Biniszkiewicz

doi:10.1117/12.413713

31 January 2001 Laser-induced fluorescent endoscopy (LIFE) in detection of malignant lesions of the colon

Wojciech Cebula, Witold Zieleznik, Aleksander Sieron, Mariusz Adamek, Aleksandra Kawczyk-Krupka, Michal Szygula, Tomasz Biniszkiewicz

Author Affiliations +

Proceedings Volume 4156, Clinical Lasers and Diagnostics; (2001) https://doi.org/10.1117/12.413713
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

110 patients were subjected to colonscopy under white light and autofluorescence. An adapted Xillix LIFE system and xenon light source with interference filter were used in the autofluorescence diagnostics. Both techniques revealed 67 small lesions, including 45 neoplastic ones and 22 others in the examined patients. The autofluorescence examination revealed 43 neoplastic changes, while conventional white-light colonscopy allowed for localization of 39 neoplastic lesions. Autofluorescent imaging of large intestine mucosa is more sensitive in the detection of small neoplastic changes than traditional colonscopy.

Citation Download Citation

Wojciech Cebula, Witold Zieleznik, Aleksander Sieron, Mariusz Adamek, Aleksandra Kawczyk-Krupka, Michal Szygula, and Tomasz Biniszkiewicz "Laser-induced fluorescent endoscopy (LIFE) in detection of malignant lesions of the colon", Proc. SPIE 4156, Clinical Lasers and Diagnostics, (31 January 2001); https://doi.org/10.1117/12.413713

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