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14 June 2002 High resolution spectroscopic optical coherence tomography in the 900-1100 nm wavelength range
Kostadinka K. Bizheva, Boris Povazay, Alexander A. Apolonski, Angelika Unterhuber, Boris Hermann, Harald Sattmann, Phillip St. J. Russell, Ferenc Krausz, Adolf Friedrich Fercher, Wolfgang Drexler
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Proceedings Volume 4619, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications VI; (2002) https://doi.org/10.1117/12.470492
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States
Abstract
We demonstrate for the first time optical coherence tomography (OCT) in the 900-1100 nm wavelength range. A photonic crystal fiber (PCF) in combination with a sub-15fs Ti:sapphire laser is used to produce an emission spectrum with an optical bandwidth of 35 nm centered at ~1070 nm. Coupling the light from the PCF based source to an optimized free space OCT system results in ~15 micrometers axial resolution in air, corresponding to ~10 micrometers in biological tissue. The near infrared wavelength range around 1100 nm is very attractive for high resolution ophthalmologic OCT imaging of the anterior and posterior eye segment with enhanced penetration. The emission spectrum of the PCF based light source can also be reshaped and tuned to cover the wavelength region around 950-970 nm, where water absorption has a local peak. Therefore, the OCT system described in this paper can also be used for spatially resolved water absorption measurements in non-transparent biological tissue. A preliminary qualitative spectroscopic Oct measurement in D2O and H2 O phantoms is described in this paper.
© (2002) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
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Kostadinka K. Bizheva, Boris Povazay, Alexander A. Apolonski, Angelika Unterhuber, Boris Hermann, Harald Sattmann, Phillip St. J. Russell, Ferenc Krausz, Adolf Friedrich Fercher, and Wolfgang Drexler "High resolution spectroscopic optical coherence tomography in the 900-1100 nm wavelength range", Proc. SPIE 4619, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications VI, (14 June 2002); https://doi.org/10.1117/12.470492
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KEYWORDS
Optical coherence tomography
Spectroscopy
Light sources
Absorption
Eye
Tissue optics
Photonic crystal fibers
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