Heat diffusion and chemical kinetics in Mark-III FEL tissue ablation

Glenn S. Edwards; M. Shane Hutson; Susanne Hauger

doi:10.1117/12.461378

1 April 2002 Heat diffusion and chemical kinetics in Mark-III FEL tissue ablation

Glenn S. Edwards, M. Shane Hutson, Susanne Hauger

Proceedings Volume 4633, Commercial and Biomedical Applications of Ultrafast and Free-Electron Lasers; (2002) https://doi.org/10.1117/12.461378
Event: High-Power Lasers and Applications, 2002, San Jose, California, United States

Abstract

We present in some detail a theoretical model that provides a dynamical account for the experimentally observed ablative properties of an FEL tuned near 6.45 microns. The model is based on thermal diffusion and chemical kinetics in a system of alternating layers of protein and saline as heated by an infrared Mark-III FEL. We compare exposure at 3.0 microns, where water is the sole absorber, to that at 6.45 microns, where both protein and water absorb. The picosecond pulses of the Mark-III superpulse are treated as a train of impulses. We consider the onset of both the helix-coil transition and chemical bond breaking in terms of the thermal, chemical, and mechanical properties of the system as well as laser wavelength and pulse structure.

Citation Download Citation

Glenn S. Edwards, M. Shane Hutson, and Susanne Hauger "Heat diffusion and chemical kinetics in Mark-III FEL tissue ablation", Proc. SPIE 4633, Commercial and Biomedical Applications of Ultrafast and Free-Electron Lasers, (1 April 2002); https://doi.org/10.1117/12.461378

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