Raman spectroscopic analysis of ionization processes in biological systems

Jennifer Conroy; Eoghan O. Faolain; Carmel Mothersill; C. Seymour; Fiona M. Lyng; Hugh James Byrne

doi:10.1117/12.463638

27 August 2003 Raman spectroscopic analysis of ionization processes in biological systems

Jennifer Conroy, Eoghan O. Faolain, Carmel Mothersill, C. Seymour, Fiona M. Lyng, Hugh James Byrne

Proceedings Volume 4876, Opto-Ireland 2002: Optics and Photonics Technologies and Applications; (2003) https://doi.org/10.1117/12.463638
Event: OPTO Ireland, 2002, Galway, Ireland

Abstract

Raman spectroscopy was employed to spectroscopically fingerprint the range of animo acids, purines and pyramidines. Irradiation of these components by 10 Gray gamma rays shows that several of the amino acids and pyrimidines are particularly prone to molecular degradation. The spectroscopic signature of the degradation is utilized to identify the molecular origin of the degradation observed in the various biological macromolecules. Irradiation in solution compared to solid sate is employed in an effort to differentiate between primary and secondary ionization processes.

Citation Download Citation

Jennifer Conroy, Eoghan O. Faolain, Carmel Mothersill, C. Seymour, Fiona M. Lyng, and Hugh James Byrne "Raman spectroscopic analysis of ionization processes in biological systems", Proc. SPIE 4876, Opto-Ireland 2002: Optics and Photonics Technologies and Applications, (27 August 2003); https://doi.org/10.1117/12.463638

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