Simplified laser fluorescence scanner for proteomics studies and early cancer diagnosis

Byeoung C. Kim; Jin H. Jeong; Dong S. Jeong; Eui Y. Choi; Jae H. Kim; Kie Bong Nahm

doi:10.1117/12.482938

12 September 2002 Simplified laser fluorescence scanner for proteomics studies and early cancer diagnosis

Byeoung C. Kim, Jin H. Jeong, Dong S. Jeong, Eui Y. Choi, Jae H. Kim, Kie Bong Nahm

Proceedings Volume 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment; (2002) https://doi.org/10.1117/12.482938
Event: Photonics Asia, 2002, Shanghai, China

Abstract

A compact integral system was developed capable of quantitatively measuring analytes in biological fluids. This system uses the fluorescence as a reporter molecule to provide the information about the molecular density of the target molecule in the test sample. Developed for the purpose of providing an affordable means of fast point–of-care testing of marker molecules specifically arranged in the specimen, this system proved to be able to detect the presence of the marker agent at the level of 50 pg/ml in less than 15 minutes, with the actual measurement taking less than 1.5 minutes. The design concept for this unit is presented together with the result for a few representative samples.

Citation Download Citation

Byeoung C. Kim, Jin H. Jeong, Dong S. Jeong, Eui Y. Choi, Jae H. Kim, and Kie Bong Nahm "Simplified laser fluorescence scanner for proteomics studies and early cancer diagnosis", Proc. SPIE 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, (12 September 2002); https://doi.org/10.1117/12.482938

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