Using optical coherence tomography (OCT) for quantitative measurement of attenuation coefficients of the arterial wall

Freek J. van der Meer; Dirk J. Faber; Maurice C.G. Aalders; Ton G. J. M. van Leeuwen

doi:10.1117/12.477883

12 September 2003 Using optical coherence tomography (OCT) for quantitative measurement of attenuation coefficients of the arterial wall

Freek J. van der Meer, Dirk J. Faber, Maurice C.G. Aalders, Ton G. J. M. van Leeuwen

Author Affiliations +

Proceedings Volume 4949, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII; (2003) https://doi.org/10.1117/12.477883
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

The feasibility to detect and characterize vulnerable plaques by Optical Coherence Tomography (OCT) is currently under investigation. It has been shown that in some cases, by using qualitative criteria, the OCT images can be used to differentiate between different types of plaque. However, the quality of the image and the experience of the observer greatly influences the interpretation of the images, which indicates the necessity of a quantitative analysis of the OCT data. As OCT measures the depth resolved backscattering it is possible to calculate the light attenuation coefficient (μ_t) in the different areas in the image and use that to identify the different plaque constituents in the target tissue. In this study, we present in vitro data on μ_t, measured in atherosclerotic lesions.

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Freek J. van der Meer, Dirk J. Faber, Maurice C.G. Aalders, and Ton G. J. M. van Leeuwen "Using optical coherence tomography (OCT) for quantitative measurement of attenuation coefficients of the arterial wall", Proc. SPIE 4949, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII, (12 September 2003); https://doi.org/10.1117/12.477883

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KEYWORDS

Optical coherence tomography

Signal attenuation

Tissue optics

Tissues

Coherence imaging

Optical properties

Arteries

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