Response of near-infrared localized reflectance signals of intact diabetic human skin to thermal stimuli

Omar S. Khalil; Shu-jen Yeh; Xaimao Wu

doi:10.1117/12.518754

13 October 2003 Response of near-infrared localized reflectance signals of intact diabetic human skin to thermal stimuli

Omar S. Khalil, Shu-jen Yeh, Xaimao Wu

Author Affiliations +

Proceedings Volume 5068, Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV; (2003) https://doi.org/10.1117/12.518754
Event: Saratov Fall Meeting 2002 Laser Physics and Photonics, Spectroscopy, and Molecular Modeling III; Coherent Optics of Ordered and Random Media III, 2002, Saratov, Russian Federation

Abstract

We studied the temperature-controlled localized reflectance of the dorsal arm of diabetic and non-diabetic subjects. The thermo-optical response of human skin at small source-detector distances is related to the diabetic status of the subject. It was possible to segregate diabetic from non-diabetic data based on the values of μa, μs^' and δ; and the change in their values (Δμa, Δμs^', and Δδ) as a function of temperature. The segregation into diabetic and non-diabetic based on the thermal response of μa, μs^' is consistent with cross-linking of vascular and tissue proteins by excess glucose during frequent hyperglycemic episodes.

Citation Download Citation

Omar S. Khalil, Shu-jen Yeh, and Xaimao Wu "Response of near-infrared localized reflectance signals of intact diabetic human skin to thermal stimuli", Proc. SPIE 5068, Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV, (13 October 2003); https://doi.org/10.1117/12.518754

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available