Vis-NIR spectroscopic and clinical evaluations of the response of spider leg veins to a high-powered pulsed-diode-laser (810 nm) therapy

Wolf-Dieter Schmidt; Helga Konrad M.D.; Armin Scheibe; Gunther Haroske; Gabriele Zimmermann; Liudmila G. Astafyeva; Uwe Wollina M.D.; Dieter Fassler

doi:10.1117/12.499150

16 October 2003 Vis-NIR spectroscopic and clinical evaluations of the response of spider leg veins to a high-powered pulsed-diode-laser (810 nm) therapy

Wolf-Dieter Schmidt, Helga Konrad M.D., Armin Scheibe, Gunther Haroske, Gabriele Zimmermann, Liudmila G. Astafyeva, Uwe Wollina M.D., Dieter Fassler

Author Affiliations +

Proceedings Volume 5142, Therapeutic Laser Applications and Laser-Tissue Interactions; (2003) https://doi.org/10.1117/12.499150
Event: European Conferences on Biomedical Optics 2003, 2003, Munich, Germany

Abstract

Spider leg veins represent an important aesthetic problem. This clinical study was performed to investigate the pulsed near-infrared diode laser (810 nm) treatment of spider leg veins. 35 female patients were enrolled in this study and treated twice with laser densities of energy (fluence) between 60 - 100 J/cm² and a spot size of 50 mm². Histological examinations were performed to investigate morphological and functional effects. Spectroscopic investigations were used as a non-invasive evaluation tool. After the first laser treatment 15 patients showed a complete disappearance (CR); in the remaining 20 patients a remarkable improvement (RI) was seen (N=35). After six months of follow-up CR was noted in 6 patients, RI in 6, a stable situation in 9, and scar formation in one patient (N=21). The histological examination before and after laser treatment showed no cellular inflammatory reactions. The mean vascular areas were significantly reduced after the laser treatments. Vis-NIR spectroscopic investigations showed almost an immediate occurrence of the haemoglobin double peak and a prompt decrease of the visible remittance after laser treatment of the skin. Pulsed diode laser therapy is a safe and effective option for the treatment of spider leg veins. Objective in vivo- monitoring by remission spectroscopy and the histology of biopsy specimens show the immediate and long-term laser effects of the irradiated skin in detail.

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Wolf-Dieter Schmidt, Helga Konrad M.D., Armin Scheibe, Gunther Haroske, Gabriele Zimmermann, Liudmila G. Astafyeva, Uwe Wollina M.D., and Dieter Fassler "Vis-NIR spectroscopic and clinical evaluations of the response of spider leg veins to a high-powered pulsed-diode-laser (810 nm) therapy", Proc. SPIE 5142, Therapeutic Laser Applications and Laser-Tissue Interactions, (16 October 2003); https://doi.org/10.1117/12.499150

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