Comparison of high and low coherence Doppler spectra for human subcutaneous blood flow diagnostics in vivo

Sergey G. Proskurin

doi:10.1117/12.584616

7 March 2005 Comparison of high and low coherence Doppler spectra for human subcutaneous blood flow diagnostics in vivo

Sergey G. Proskurin

Proceedings Volume 5702, Optical Diagnostics and Sensing V; (2005) https://doi.org/10.1117/12.584616
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

Experimental methods of coherence-gated time domain imaging (TD-OCT), Doppler OCT and quasielastic laser light scattering are compared in terms of optimal data acquisition and processing. Low coherence methods are applied for flow visualization in hydrodynamic phantoms and in vivo. Low coherence reflection Doppler spectra are compared with laser Doppler spectra. Structural images of in vivo human subcutaneous veins with diameter of about 1 mm are demonstrated before and after optical clearing and raster averaging. Structural images of human thumb nail and ~1 mm in depth tissue underneath in the transitional OCT mode are presented. Low power rapid scanning optical delay line in the reference arm and low numerical aperture in the sample arm of the interferometer, along with tissue optical clearing were applied for increasing transcutaneous coherence probing depth up to 1.5 - 1.6 mm.

Citation Download Citation

Sergey G. Proskurin "Comparison of high and low coherence Doppler spectra for human subcutaneous blood flow diagnostics in vivo", Proc. SPIE 5702, Optical Diagnostics and Sensing V, (7 March 2005); https://doi.org/10.1117/12.584616

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