Paper
8 September 2006 Photo-responsive hydrogel for controlling flow on a microfluidic chip
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Proceedings Volume 6343, Photonics North 2006; 63432R (2006) https://doi.org/10.1117/12.707765
Event: Photonics North 2006, 2006, Quebec City, Canada
Abstract
One technological challenge in microfluidic system design has been controlling the directional flow of minute amounts of fluid through various narrow channels. Stimuli-responsive polymers can be used as micro control devices such as valves because these materials significantly change their volumetric properties in response to small environmental changes in pH, temperature, solvent composition, or electric field. In this paper, a bi-layered hydrogel structure is introduced as a light activated microactuator. The first layer of the device is a light sensitive polymer network containing poly(vinyl alcohol) (PVA) and the retinal protein bacteriorhodopsin (bR). The second layer is a blend of PVA hydrogel and a pH sensitive polymer polyethylenimine (PEI). When exposed to a light source with a peak response at 568 nm, the bR molecules in the first layer undergo a multistage photocycle that cause protons to be pumped into the surrounding medium. The diffusion of these similarly charged ions through the adjoining pH responsive hydrogel generates electrostatic repulsive and attractive forces which alter the osmotic pressure within the cross-linked polymer network. Depending upon the type of electrostatic forces generated, the pH sensitive hydrogel layer will swell or, alternatively, collapse. The multi-layered structure can be fabricated and inserted into the microchannel. The expanding volume of the actuating hydrogel is used to regulate flow or control leakage. Preliminary experiments on a 625mm3 optical actuating device are presented to identify key response characteristics and illustrate the mechanism for actuation
© (2006) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Khaled Al-Aribe, George K. Knopf, and Amarjeet S. Bassi "Photo-responsive hydrogel for controlling flow on a microfluidic chip", Proc. SPIE 6343, Photonics North 2006, 63432R (8 September 2006); https://doi.org/10.1117/12.707765
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Cited by 7 scholarly publications.
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KEYWORDS
Microfluidics

Actuators

Polymers

Molecules

Proteins

Ions

Light sources

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