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3 November 2006 Time-resolved fluorescence measurements for diffuse optical tomography using ultrafast time-correlated single photon counting
Yves Bérubé-Lauzière, Vincent Robichaud
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Proceedings Volume 6372, Advanced Photon Counting Techniques; 637206 (2006) https://doi.org/10.1117/12.685421
Event: Optics East 2006, 2006, Boston, Massachusetts, United States
Abstract
We develop a novel approach to infer depth information about a small fluorophore-filled inclusion immersed in a scattering medium. It relies on time-resolved measurements of the time of flight distribution of emitted fluorescent photons after short pulse laser excitation. The approach uses a novel numerical constant fraction discrimination technique to assign a stable arrival time to the distribution's early photons. Our experimental results show a linear relationship between these arrival times and the position of the inclusion. This approach will serve as a useful technique in fluorescence diffuse optical tomography.
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Yves Bérubé-Lauzière and Vincent Robichaud "Time-resolved fluorescence measurements for diffuse optical tomography using ultrafast time-correlated single photon counting", Proc. SPIE 6372, Advanced Photon Counting Techniques, 637206 (3 November 2006); https://doi.org/10.1117/12.685421
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Cited by 6 scholarly publications.
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KEYWORDS
Photons
Sensors
Luminescence
Diffuse optical tomography
Optical filters
Pulsed laser operation
Scattering
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