Three-dimensional imaging of eye surface pathologies and contact lens fit with high resolution spectral optical coherence tomography

M. Wojtkowski; B. Kałużny M.D.; A. Szkulmowska; T. Bajraszewski; M. Szkulmowski; P. Targowski; A. Kowalczyk

doi:10.1117/12.698992

5 March 2007 Three-dimensional imaging of eye surface pathologies and contact lens fit with high resolution spectral optical coherence tomography

M. Wojtkowski, B. Kałużny M.D., A. Szkulmowska, T. Bajraszewski, M. Szkulmowski, P. Targowski, A. Kowalczyk

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Proceedings Volume 6426, Ophthalmic Technologies XVII; 64260S (2007) https://doi.org/10.1117/12.698992
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

Purpose: To show potential of Spectral Optical Coherence Tomography system for high resolution, cross-sectional and three-dimensional imaging of eye surface pathologies. Methods: High-speed spectral OCT prototype instrument with 4.5 &mgr;m axial resolution was designed and constructed for clinical use. Measurements of anterior segment of human eye have been performed in ophthalmology clinic on 86 patients suffering various eye surface disorders including corneal dystrophies, corneal scars, conjunctival folds, keratoconus, bullus keratopathy, filtration blebs and other post-operative changes. Additionally, examinations of contact lens fit on 97 healthy corneas have been performed up to date. Results: High quality, high resolution cross-sectional images and three-dimensional reconstructions of cornea, conjunctiva and sclera of pathologic eyes together with examples of numerical analysis including segmentation of fluid in filtration blebs, scars and deposits are shown. Quantitative analysis of contact lens fit is demonstrated.

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M. Wojtkowski, B. Kałużny M.D., A. Szkulmowska, T. Bajraszewski, M. Szkulmowski, P. Targowski, and A. Kowalczyk "Three-dimensional imaging of eye surface pathologies and contact lens fit with high resolution spectral optical coherence tomography", Proc. SPIE 6426, Ophthalmic Technologies XVII, 64260S (5 March 2007); https://doi.org/10.1117/12.698992

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KEYWORDS

Optical coherence tomography

Eye

Imaging systems

Cornea

3D image processing

Image segmentation

Image resolution

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