Anatomically constrained maximum likelihood estimation for estimating retinal thickness from scanning laser ophthalmoscope data

Tim Holmes; Brian Northan; Gerhard Zinser; Natalie Hutchings; Ying Li; Dirk-Uwe Bartsch; John Flanagan

doi:10.1117/12.709453

29 March 2007 Anatomically constrained maximum likelihood estimation for estimating retinal thickness from scanning laser ophthalmoscope data

Tim Holmes, Brian Northan, Gerhard Zinser, Natalie Hutchings, Ying Li, Dirk-Uwe Bartsch, John Flanagan

Author Affiliations +

Proceedings Volume 6514, Medical Imaging 2007: Computer-Aided Diagnosis; 651419 (2007) https://doi.org/10.1117/12.709453
Event: Medical Imaging, 2007, San Diego, CA, United States

Abstract

A multistage algorithm is presented, whose components are based upon maximum likelihood estimation (MLE). From 3D scanning laser ophthalmoscope (SLO) image data, the algorithm finds the positions of the two anatomical boundaries of the eye's fundus that define the retina, which are the internal limiting membrane (ILM) and the retinal pigment epithelium (RPE). he retinal thickness is then calculated by subtraction. Retinal thickness is useful for indicating, assessing risk of, and following several diseases, including various forms of macular edema and cysts.

Citation Download Citation

Tim Holmes, Brian Northan, Gerhard Zinser, Natalie Hutchings, Ying Li, Dirk-Uwe Bartsch, and John Flanagan "Anatomically constrained maximum likelihood estimation for estimating retinal thickness from scanning laser ophthalmoscope data", Proc. SPIE 6514, Medical Imaging 2007: Computer-Aided Diagnosis, 651419 (29 March 2007); https://doi.org/10.1117/12.709453

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
11 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Optical coherence tomography

Scanning laser ophthalmoscopy

Eye

Retina

Point spread functions

Scanning laser ophthalmoscopes

Algorithm development

Show All Keywords

Keywords/Phrases

Search In:

Publication Years