Novel method for depth-resolved brain functional imaging by time-domain NIRS

Davide Contini; Lorenzo Spinelli; Alessandro Torricelli; Antonio Pifferi; Rinaldo Cubeddu

doi:10.1117/12.728104

12 July 2007 Novel method for depth-resolved brain functional imaging by time-domain NIRS

Davide Contini, Lorenzo Spinelli, Alessandro Torricelli, Antonio Pifferi, Rinaldo Cubeddu

Proceedings Volume 6629, Diffuse Optical Imaging of Tissue; 662908 (2007) https://doi.org/10.1117/12.728104
Event: European Conferences on Biomedical Optics, 2007, Munich, Germany

Abstract

A novel approach to improve depth selectivity based on time-domain contrast functions is presented. The method was tested with Monte Carlo simulations showing sensitivity to absorption changes of deep inclusions and improved rejection of superficial effects. Preliminary in-vivo measurements were performed on healthy volunteer during a Valsalva maneuver and during finger tapping discriminating brain cortex activation from hemodynamic changes associated to systemic effects in the scalp.

Citation Download Citation

Davide Contini, Lorenzo Spinelli, Alessandro Torricelli, Antonio Pifferi, and Rinaldo Cubeddu "Novel method for depth-resolved brain functional imaging by time-domain NIRS", Proc. SPIE 6629, Diffuse Optical Imaging of Tissue, 662908 (12 July 2007); https://doi.org/10.1117/12.728104

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