Paper
30 April 2008 Plasmonic sensors based on nano-holes: technology and integration
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Abstract
Surface plasmon resonance sensors are a popular technology for the optical detection of surface adsorption, for applications ranging from drug-development to pathogen detection. Here, we will discuss the integration of nano-hole arrays to provide high-sensitivity detection, with a lower detection limit, speed and cost. Calculations will be presented that suggest that in-hole detection is more sensitive than detecting binding from the surface around the nano-holes. In-hole detection also has the benefit of increased speed due to rapid diffusive transport, yet it provides the challenge of microfluidic/nanofluidic integration. We will outline our recent efforts to produce nano-hole arrays with through-hole detection.
© (2008) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
R. Gordon, D. Sinton, A. G. Brolo, and K. L. Kavanagh "Plasmonic sensors based on nano-holes: technology and integration", Proc. SPIE 6959, Micro (MEMS) and Nanotechnologies for Space, Defense, and Security II, 695913 (30 April 2008); https://doi.org/10.1117/12.777681
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CITATIONS
Cited by 8 scholarly publications and 6 patents.
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KEYWORDS
Microfluidics

Surface plasmons

Gold

Sensors

Metals

Adsorption

Detector arrays

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