Stimulatory effect of low-level GaAlAs laser (808 nm) on bone defect created surgically in rabbit femur

Qiushi Li; Zhou Qu

doi:10.1117/12.835041

28 August 2009 Stimulatory effect of low-level GaAlAs laser (808 nm) on bone defect created surgically in rabbit femur

Qiushi Li, Zhou Qu

Proceedings Volume 7382, International Symposium on Photoelectronic Detection and Imaging 2009: Laser Sensing and Imaging; 73820Q (2009) https://doi.org/10.1117/12.835041
Event: International Symposium on Photoelectronic Detection and Imaging 2009, 2009, Beijing, China

Abstract

Recently, low-level laser therapy (LLLT) has been reported to have a photobiomodulation effect on bio-tissues. Our aim was to evaluate the effect of low level GaAlAs laser on bone regeneration around bone defect sites created surgically in rabbit femur. Thirty rabbits were randomly divided into an experimental and a control groups. A GaAlAs semiconductor diode laser was applied in the experimental group( λ = 808nm, P =75mW, (symbol) =0.4mm,t=5min, _ρE=28J/cm²)immediately after surgery once a day for 3 consecutive days with no irradiation in the control group. Rabbits were sacrificed on the 7th, 14th, 21th days after surgery (DAS) and femur samples were prepared for bone histomorphometry analysis. The results showed that the bone volume, the osteoid volume, osteoblast surface and the mineral apposition rate in the laser group were higher statistically (P<0.05) than those indices in the control group at different periods. These data revealed that LLLT can enhance bone regeneration. LLLT seems to have a clinical application in promoting bone healing around implant in the future.

Citation Download Citation

Qiushi Li and Zhou Qu "Stimulatory effect of low-level GaAlAs laser (808 nm) on bone defect created surgically in rabbit femur", Proc. SPIE 7382, International Symposium on Photoelectronic Detection and Imaging 2009: Laser Sensing and Imaging, 73820Q (28 August 2009); https://doi.org/10.1117/12.835041

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