Optimal waveband and mathematical model for analysis of human whole blood glucose by near infrared transmission spectroscopy

Furong Huang; Jianhui Yu; Shiping Li; Dongming Wang; Yunhan Luo; Shifu Zheng

doi:10.1117/12.864035

11 October 2010 Optimal waveband and mathematical model for analysis of human whole blood glucose by near infrared transmission spectroscopy

Furong Huang, Jianhui Yu, Shiping Li, Dongming Wang, Yunhan Luo, Shifu Zheng

Author Affiliations +

Proceedings Volume 7656, 5th International Symposium on Advanced Optical Manufacturing and Testing Technologies: Optical Test and Measurement Technology and Equipment; 76566W (2010) https://doi.org/10.1117/12.864035
Event: 5th International Symposium on Advanced Optical Manufacturing and Testing Technologies, 2010, Dalian, China

Abstract

The optimal waveband for quantitative analysis of the human whole blood glucose by near infrared transmission spectroscopy is discussed in this paper. First, whole blood samples of different thickness (0.5mm, 1mm, 2mm, 4mm ) of the near-infrared transmittance spectra were analyzed respectively. It shows that the sample thickness of 0.5mm is more suitable for spectral analysis. And then near infrared spectroscopy of 111 samples of 0.5mm thickness were collected. Finally, different pretreatment methods of scattering correction methods, derivatives and different modeling spectral regions were compared to find out their impact on mathematical prediction model. The result shows that the best prediction accuracy was obtained in the waveband of 1500~1900nm by using Standard Normal Variate(SNV),the second derivative spectra and Partial Least Square (PLS) regression. And the correlation coefficient(RP), the Root Mean Square Error of Prediction(RMSEP) and the Relative Root Mean square Error of Prediction(RRMSEP) for the corresponding model are 0.836, 0.271, 5.519%, respectively.

Citation Download Citation

Furong Huang, Jianhui Yu, Shiping Li, Dongming Wang, Yunhan Luo, and Shifu Zheng "Optimal waveband and mathematical model for analysis of human whole blood glucose by near infrared transmission spectroscopy", Proc. SPIE 7656, 5th International Symposium on Advanced Optical Manufacturing and Testing Technologies: Optical Test and Measurement Technology and Equipment, 76566W (11 October 2010); https://doi.org/10.1117/12.864035

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available