Towards single cell spectroscopy and refractometry in microfluidic chip platforms

J. B. Tillak; I. Bernacka-Wojcik; D. Barata; P. A. S. Jorge; H. Águas; A. G. Oliva

doi:10.1117/12.892180

26 July 2011 Towards single cell spectroscopy and refractometry in microfluidic chip platforms

J. B. Tillak, I. Bernacka-Wojcik, D. Barata, P. A. S. Jorge, H. Águas, A. G. Oliva

Proceedings Volume 8001, International Conference on Applications of Optics and Photonics; 800112 (2011) https://doi.org/10.1117/12.892180
Event: International Conference on Applications of Optics and Photonics, 2011, Braga, Portugal

Abstract

This paper evaluates various strategies proposed for single cell refractometry and spectroscopy using fiber optic sensors and microfluidic chips. Details concerning design, fabrication and characterization of the chips will be addressed. Preliminary results obtained with alternative on-chip configurations using combination of fiber Bragg gratings with mirrored single mode and multimode fibers will be presented indicating the possibility of performing simultaneous assessment of cellular refractive index and absorption properties.

Citation Download Citation

J. B. Tillak, I. Bernacka-Wojcik, D. Barata, P. A. S. Jorge, H. Águas, and A. G. Oliva "Towards single cell spectroscopy and refractometry in microfluidic chip platforms", Proc. SPIE 8001, International Conference on Applications of Optics and Photonics, 800112 (26 July 2011); https://doi.org/10.1117/12.892180

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