Imaging of the interaction of low frequency electric fields with biological tissues by optical coherence tomography

Adrian F. Peña; Jack Devine; Alexander Doronin; Igor Meglinski

doi:10.1117/12.2040842

4 March 2014 Imaging of the interaction of low frequency electric fields with biological tissues by optical coherence tomography

Adrian F. Peña, Jack Devine, Alexander Doronin, Igor Meglinski

Author Affiliations +

Proceedings Volume 8934, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII; 89341C (2014) https://doi.org/10.1117/12.2040842
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

We report the use of conventional Optical Coherence Tomography (OCT) for visualization of propagation of low frequency electric field in soft biological tissues ex vivo. To increase the overall quality of the experimental images an adaptive Wiener filtering technique has been employed. Fourier domain correlation has been subsequently applied to enhance spatial resolution of images of biological tissues influenced by low frequency electric field. Image processing has been performed on Graphics Processing Units (GPUs) utilizing Compute Unified Device Architecture (CUDA) framework in the frequencydomain. The results show that variation in voltage and frequency of the applied electric field relates exponentially to the magnitude of its influence on biological tissue. The magnitude of influence is about twice more for fresh tissue samples in comparison to non-fresh ones. The obtained results suggest that OCT can be used for observation and quantitative evaluation of the electro-kinetic changes in biological tissues under different physiological conditions, functional electrical stimulation, and potentially can be used non-invasively for food quality control.

Citation Download Citation

Adrian F. Peña, Jack Devine, Alexander Doronin, and Igor Meglinski "Imaging of the interaction of low frequency electric fields with biological tissues by optical coherence tomography", Proc. SPIE 8934, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII, 89341C (4 March 2014); https://doi.org/10.1117/12.2040842

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
7 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Optical coherence tomography

Tissues

Image filtering

Electronic filtering

Filtering (signal processing)

Image processing

Breast

Show All Keywords

Keywords/Phrases

Search In:

Publication Years