To the problem of stiffness-contrast quantification in the correlation-stability approach to OCT elastography

Lev A. Matveev; Vladimir Yu. Zaitsev; Alexandr L. Matveyev; Grigory V. Gelikonov; Valentin M. Gelikonov

doi:10.1117/12.2049516

30 January 2014 To the problem of stiffness-contrast quantification in the correlation-stability approach to OCT elastography

Lev A. Matveev, Vladimir Yu. Zaitsev, Alexandr L. Matveyev, Grigory V. Gelikonov, Valentin M. Gelikonov

Author Affiliations +

Proceedings Volume 9031, Saratov Fall Meeting 2013: Optical Technologies in Biophysics and Medicine XV; and Laser Physics and Photonics XV; 903102 (2014) https://doi.org/10.1117/12.2049516
Event: Saratov Fall Meeting 2013, 2013, Saratov, Russian Federation

Abstract

In the initial variant, the recently proposed correlation-stability approach to elasticity mapping in optical coherence tomography (OCT) of tissues was intended for qualitative visualization of the relative stiffness of different regions in tissue. Further development of this approach is aimed at obtaining the stiffness ratio between different tissue regions. In the proposed modified variant, the correlation-stability approach has much in common with the speckle variance approach which is used for visualizing blood microcirculation in OCT. We present preliminary demonstrations of implementation of the modified correlation-stability approach to quantify the relative stiffness using processing of the speckle-structure variability of OCT images of deformed tissues.

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Lev A. Matveev, Vladimir Yu. Zaitsev, Alexandr L. Matveyev, Grigory V. Gelikonov, and Valentin M. Gelikonov "To the problem of stiffness-contrast quantification in the correlation-stability approach to OCT elastography", Proc. SPIE 9031, Saratov Fall Meeting 2013: Optical Technologies in Biophysics and Medicine XV; and Laser Physics and Photonics XV, 903102 (30 January 2014); https://doi.org/10.1117/12.2049516

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