Plasmon assisted optical trapping: fundamentals and biomedical applications

Alexandros A. Serafetinides; Mersini Makropoulou; Georgios N. Tsigaridas; Anastasios Gousetis

doi:10.1117/12.2178248

8 January 2015 Plasmon assisted optical trapping: fundamentals and biomedical applications

Alexandros A. Serafetinides, Mersini Makropoulou, Georgios N. Tsigaridas, Anastasios Gousetis

Proceedings Volume 9447, 18th International School on Quantum Electronics: Laser Physics and Applications; 94470V (2015) https://doi.org/10.1117/12.2178248
Event: Eighteenth International School on Quantum Electronics: Laser Physics and Applications, 2014, Sozopol, Bulgaria

Abstract

The field of optical trapping has dramatically grown due to implementation in various arenas including physics, biology, medicine and nanotechnology. Certainly, optical tweezers are an invaluable tool to manipulate a variation of particles, such as small dielectric spheres, cells, bacteria, chromosomes and even genes, by highly focused laser beams through microscope. As the main disadvantage of the conventional optical trapping systems is the diffraction limit of the incident light, plasmon assisted nanotrapping is reported as a suitable technique for trapping sub-wavelength metallic or dielectric particles. In this work, firstly, we report briefly on the basic theory of plasmon excitation, focusing on the interaction of nanoscale metallic structures with laser light. Secondly, experimental and numerical simulation results are also presented, demonstrating enhancement of the trapping efficiency of glass or SiO2 substrates, coated with Au and Ag nanostructures, with or without nanoparticles. The optical forces were calculated by measuring the particle’s escape velocity calibration method. Finally, representative applications of plasmon assisted optical trapping are reviewed, from cancer therapeutics to fundamental biology and cell nanosurgery.

Citation Download Citation

Alexandros A. Serafetinides, Mersini Makropoulou, Georgios N. Tsigaridas, and Anastasios Gousetis "Plasmon assisted optical trapping: fundamentals and biomedical applications", Proc. SPIE 9447, 18th International School on Quantum Electronics: Laser Physics and Applications, 94470V (8 January 2015); https://doi.org/10.1117/12.2178248

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