Continuous imaging of the blood vessels in tumor mouse dorsal skin window chamber model by using SD-OCT

Xiao Peng; Shaozhuang Yang; Bin Yu; Qi Wang; Danying Lin; Jian Gao; Peiqi Zhang; Yiqun Ma; Junle Qu; Hanben Niu

doi:10.1117/12.2213134

8 March 2016 Continuous imaging of the blood vessels in tumor mouse dorsal skin window chamber model by using SD-OCT

Xiao Peng, Shaozhuang Yang, Bin Yu, Qi Wang, Danying Lin, Jian Gao, Peiqi Zhang, Yiqun Ma, Junle Qu, Hanben Niu

Proceedings Volume 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX; 96973N (2016) https://doi.org/10.1117/12.2213134
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Optical Coherence Tomography (OCT) has been widely applied into microstructure imaging of tissues or blood vessels with a series of advantages, including non-destructiveness, real-time imaging, high resolution and high sensitivity. In this study, a Spectral Domain OCT (SD-OCT) system with higher sensitivity and signal-to-noise ratio (SNR) was built up, which was used to observe the blood vessel distribution and blood flow in the dorsal skin window chamber of the nude mouse tumor model. In order to obtain comparable data, the distribution images of blood vessels were collected from the same mouse before and after tumor injection. In conclusion, in vivo blood vessel distribution images of the tumor mouse model have been continuously obtained during around two weeks.

Citation Download Citation

Xiao Peng, Shaozhuang Yang, Bin Yu, Qi Wang, Danying Lin, Jian Gao, Peiqi Zhang, Yiqun Ma, Junle Qu, and Hanben Niu "Continuous imaging of the blood vessels in tumor mouse dorsal skin window chamber model by using SD-OCT", Proc. SPIE 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX, 96973N (8 March 2016); https://doi.org/10.1117/12.2213134

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