Optically induced microbubbles around gold nanorods: the influence of particle parameters and environment on cavitation threshold

Lucia Cavigli; Fulvio Ratto; Marella de Angelis; Sonia Centi; Sarah Lai; Alberto Cini; Claudia Borri; Stefano Colagrande; Roberto Pini

doi:10.1117/12.2212340

15 March 2016 Optically induced microbubbles around gold nanorods: the influence of particle parameters and environment on cavitation threshold

Lucia Cavigli, Fulvio Ratto, Marella de Angelis, Sonia Centi, Sarah Lai, Alberto Cini, Claudia Borri, Stefano Colagrande, Roberto Pini

Author Affiliations +

Proceedings Volume 9708, Photons Plus Ultrasound: Imaging and Sensing 2016; 970849 (2016) https://doi.org/10.1117/12.2212340
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Photoacoustic imaging (PAI) and microsurgery are attracting interest for cancer treatment. The absorption of light triggers thermoelastic processes that cause ultrasound emission and even cavitation. The ultrasounds emission is exploited to reconstruct images, the cavitation may be used to destroy malignant cells. Gold nanorods (GNRs) have been investigated as contrast agents for PAI, but still little is known about the trigger of cavitation processes. Here we study the influence of GNRs parameters, such as their size, coating and environment, on the cavitation threshold. We expect these results will provide useful indications to develop new theranostics techniques based on light-ultrasound interaction

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Lucia Cavigli, Fulvio Ratto, Marella de Angelis, Sonia Centi, Sarah Lai, Alberto Cini, Claudia Borri, Stefano Colagrande, and Roberto Pini "Optically induced microbubbles around gold nanorods: the influence of particle parameters and environment on cavitation threshold", Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 970849 (15 March 2016); https://doi.org/10.1117/12.2212340

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